Ohio State vs. Indiana prediction, pick, odds, spread: No. 1 Buckeyes, No. 2 Hoosiers collide from Indy A Big Ten Championship and No. 1 seed in the College Football Playoff are on the line Saturday Original Source: https://www.cbssports.com/college-football/news/ohio-state-indiana-prediction-pick-odds-spread-where-to-watch-live-big-ten-championship-game/ Previous article: Texas Tech vs. BYU prediction, pick, odds, spread: Red Raiders, Cougars set for rematch to decide Big 12 title Prev Next article: Alabama vs. Georgia prediction, odds, time: 2025 SEC Championship Game picks by advanced model Next
![](/<img src="https://sportshub.cbsistatic.com/i/2025/12/04/3ac1376e-8331-4552-b7f6-9bbbd065b128/jeremiah-smith-ohio-state-vs-indiana-2024.jpg" title="">)