Duke vs. Florida odds, prediction, time: 2025 ACC/SEC Challenge picks from proven model SportsLine's model simulated the Duke Blue Devils vs. Florida Gators 10,000 times and revealed its 2025 ACC/SEC Challenge predictions Original Source: https://www.cbssports.com/college-basketball/news/duke-florida-odds-prediction-time-2025-acc-sec-challenge-college-basketball-picks/ Previous article: NFL Week 14 picks and score predictions: Cowboys shock Lions, Bengals stun Bills, Packers edge Bears Prev Next article: North Carolina vs. Kentucky odds, prediction: 2025 ACC/SEC Challenge picks from proven model Next
![](/<img src="https://sportshub.cbsistatic.com/i/2025/11/04/f81d2634-ddb2-45ed-ad37-136bf5264097/cameron-boozer-nikolas-khamenia-duke-blue-devils-imagn-images.jpg" title="">)